Dr. Siva Bandi Postdoctoral Researcher since May 2018 Téléphone : +41 32 718 24 66 bandi.siva[at]unine.ch

Biography

Bandi Siva (born in 1985) received a master’s degree in Organic Chemistry (2007) from Kakatiya University in India. Later he joined at GVK Bioscience pvt Ltd, India, as senior chemist in the medicinal chemistry division for drug development. In 2010 he succeeded in/won the the National eligibility test of the University Grants Commission, New Delhi, India and joined the Indian Institute of Chemical Technology for his PhD research  in Natural Product Chemistry and Medicinal Chemistry under the supervision of Dr. K. Suresh Babu. His Ph.D. thesis (2010) entitled “Phytochemical and Synthetic studies on limonoids from Indian Medicinal plant Cipadessa baccifera”. During his doctoral research, he performed bioassay guided fractionation and isolation of new bioactive compounds from Indian medicinal plants by using modern spectroscopic methods (1D & 2D NMR, LC-MS etc.). He also performed a 3 months internship on the phytochemistry of lichens at the University of Rennes, France. Later he joined in the project for phytochemical analysis in the development of ethnomedicine in IICT, Hyderabad. In April 2017, he was selected for the prestigious CSIR- Research Associate (Post Doc) from CSIR, India. During this period, he was involved in the isolation, development of fingerprint analysis and metabolic profiles of active extracts from lichens using HPTLC, UPLC-MS and UPLC-qToF MS/MS.

In May 2018, he joined the laboratory for bioanalytical chemistry at UniNE as a Postdoctoral researcher. His major research interests include natural product research in human health care, chemical ecology, and the development of new techniques for the identification of new compounds by spectroscopic and chromatographic analysis.

Project: Comparative analysis of secondary metabolism in Caenorhabditis nematodes

PUBLICATIONS

27] Ascaroside Signaling in the Bacterivorous Nematode Caenorhabditis remanei Encodes the Growth Phase of its Bacterial Food Source. Dolke*, F., Dong*, C., Bandi, S., Paetz, C., Glauser, G., von Reuss, S. H. (2019). Organic Letters; in press: https://doi.org/10.1021/acs.orglett.9b01914.

[26] UPLC–MS/MS quantitative analysis and structural fragmentation study of five Parmotrema lichens from the Eastern Ghats. Kumar, K¹., Siva, B¹., Sarma, V.U.M., Satish, M., Reddy, A.M., Boustie, J., Ashok, K.T., RamaRao, N., Suresh Babu.(2018) Journal of Pharmaceutical and Biomedical Analysis 156, 45-57. (1 = Equal contribution)

[25] Rapid identification of limonoids from Cipadessa baccifera and Xylocarpus granatum using ESI-Q-ToF-MS/MS and their structure-fragmentation study. Kumar,K¹.,  Siva, B¹., RamaRao, N., Suresh Babu, K.(2018) Journal of Pharmaceutical and Biomedical Analysis 152,224-233. (1 = Equal contribution)

[24] Synthesis and biological evaluation of Schizandrin derivatives as potential anti-cancer agents. Devi, A¹.Siva, B¹., Poornima, B., Sirisha, K., Sarma, A.V.S.  Nayak, V.L., Ashok, K. T.,  Purushotham,U., Suresh Babu, K.(2018) European Journal of Medicinal Chemistry 149, 182-192. (1 = Equal contribution)

[23] Towards the Total Synthesis of Schisandrene: Stereoselective Synthesis of the Dibenzocyclooctadiene Lignan Core. Venkanna, A., Poornima, B., Siva,B., Hari Babu, B., Suresh Babu, K. (2018) Synlett 29, 908-9011.

[22] “Click” reaction based synthesis of nimbolide derivatives and study of their insect antifeedant activity against Spodoptera litura Larvae.  Siva, B., Devi, A., Venkanna, A., Poornima, B., Sukumar, G., Divya Reddy, S.,Vijaya, M., Ramesh, U., Suresh Babu, K., Fitoterapia (2017) 123, 1- 8.

[21] Anti-proliferative and antioxidant activities of 1-methoxy-3-methyl-8-hydroxy-anthraquinone, a hydroxyanthraquinoid extrolite produced by Amycolatopsis thermoflava strain SFMA-103; Kumar, G. C., Poornima, M., Chandrasekhar, C., Poornachandra, Y.,Siva,B., Suresh Babu, K., Ramakrishna, K. V. S. Microbiology and Biotechnology Letters (2017) 45, 200-208.

[20] Novel Gomisin B Analogues as Potential cytotoxic Agents: Design, Synthesis, Biological evaluation and Docking Studies, Poornima, B., Siva, B., Venkanna, A., Shankaraiah, G., Nishant, J., Yadav, K. D., Misra, S., Suresh Babu, K. European Journal of Medicinal Chemistry, (2017) 139, 441- 453.

[19] New Cycloartane type-Triterpenoids from the areal parts of Caragana sukiensis and their biological activities, Divya Reddy, S1., Siva,B1., Phani Babu, V.S.,  Vijaya, M., Lakshma Nayak, V., Ashok, K. T., Reeta, M., Shashikala, P., Suresh Babu, K. European Journal of Medicinal Chemistry (2017) 136, 74-84(1 = Equal contribution)

[18] Synthesis and evaluation of anti-plasmodial and cytotoxic activities of epoxyazadiradione derivatives, Ashok, Y.P., Kumar, P. Ch., Siva,B., Suresh Babu, K.,  Aparna Devi, A., Puran Singh, S., Veerabhdra Rao, A. European Journal of Medicinal Chemistry (2017) 134, 242-257.

[17] Biological evaluation of 3-hydroxybenzyl alcohol, an extrolite produced by Aspergillus nidulans strain KZR-132. Ganesh, K., Poornima, M., Sujitha, P., Shiva, B., Suresh Babu, K., Ramakrishna, K.V.S.  Journal of Applied Microbiology (2017) 122, 1518-1528.

[16] New Limonoids from seeds of Cipadessa baccifera: Isolation, synthesis and their antiproliferative activities, Siva,B., Venkanna, A., Poornima, B., Boustie, J.,  Bastien, S., Venkata Rao, V.,  Jain,N.,Usha Rani, P., Suresh Babu, K. Fitoterapia (2017) 117, 34–40.

[15] Minor pyranonaphthoquinones from the apothecia of the lichen Ophioparma ventosa, Le Pogam, P., Le  Lamer, A.-C., Siva, B.,  Legouin, B., Bondon, A., Jacquemin, D., Uriac, P., Rouaud, I., Ferron, S., Obermayer, W., Suresh Babu, K., Boustie,J. Journal of Natural Products (2016) 79, 1005−1011.

[14] Total Synthesis, Biological Evaluation of Dendrodolides A-D and their Analogues; Poornima, B., Venkanna, A., Swetha, B., Karthik reddy, K., Siva,B., Phani, V. S.,   Ramesh, U.,  Suresh Babu, K. Tetrahedron (2016) 72,  4789- 4797.

[13] Synthesis and Anti-proliferative Activity of Schisantherin A analogues, Venkanna, A., Kumar, P. Ch., Poornima, B., Siva,B., Soujanya, P.,  Nishant, J., Suresh Babu, K. Medicinal Chemistry Communication, (2016) 7, 1159-1170.

[12] New Advanced glycation end-products inhibitors from Schisandra grandiflora. Poornima, B.,Anand Kumar, D., Siva,B., Venkanna, A., Tiwari,A. K.,  Suresh Babu, K. Natural Products Research (2016) 30, 493-496.

[11] Novel  Cycloartane Triterpenoids from the Nepal Native Plant Caragana  sukiensis,  Reeta, M., Siva,B., Phani Babu, V.S., Suresh Babu, K.,  Jagadeesh, B., Ranjit, R., Shrestha,K.,Gewali, M.B. Bioorganic& Medicinal Chemistry Letters (2015) 25, 5168-5171.

[10] Novel Sesquiterpenes from Schisandra grandiflora: Isolation, Cytotoxic activity and Synthesis of their triazole derivatives using “Click” reaction; Poornima, B., Siva,B., Shankaraiah, G.,  Venkanna, A.,  Lakshma Nayak, V., Venkata Rao, C., Suresh Babu, K. European Journal of Medicinal Chemistry (2015) 92, 449-458.

[9] New free radical scavenging neolignans from the fruits of Piper attenuatum, Divya Reddy, S.,  Siva,B., Poornima, B., Anand Kumar, D., Ramesh, U.,  Tiwari, A. K., Suresh Babu, K. Pharmacognosy Magazine (2015) 11, 235-241.

[8] Methyl angolensate and Mexicanolide-Type Limonoids from the seeds of Cipadessa baccifera; Siva, B., Poornima, B., Venkanna, A., Rajendra Prasad, K., Sreedhar,B.,Lakshma Nayak,V., Ramakrishna, S., Suresh Babu, K. Photochemistry(2014) 98, 174-182.

[7] Phytochemical investigation of sesquiterpenes from the fruits of Schisandra chinensis and their cytotoxic activity; Venkanna, A., Siva,B., Poornima, B., Rao, P.R.V., Rajendra Prasad, K., Ashok Reddy, K., Bhanu Prakash Reddy, G.,  Suresh Babu, K., Madhusudana Rao, J., Fitoterapia (2014) 95, 102-108.

[6] The first stereoselective synthesis of dendrodolide A; Venkanna, A., Siva, B.,Poornima, B., Suresh Babu, K.,Madhusudana Rao, J. Tetrahedron Letters (2014) 55, 403-406.

[5] Cipadessin-type limonoids from the leaves of Cipadessa baccifera, Siva,B., Suresh, G., Poornima, B., Venkanna, A., Suresh Babu, K.,Rajendra Prasad,K.,Prasanna Anjaneya Reddy, L., Sreedhar, A.S., Venkata Rao, C., Tetrahedron Letters (2013) 54, 2934-2937.

[4] Studies directed towards Total Synthesis of Koshikalide: Stereoselective Synthesis of macrocyclic core, Venkanna, A., Sreedhar, E., Siva,B., Suresh Babu, K., Rajendra Prasad, K.,Madhusudana Rao, J.Tetrahedron: Asymmetry (2013) 24, 1010–1022.

[3] Cytotoxic sesquiterpenes from Hedychium spicatum: Isolation, structure elucidation and structure-activity relationship studies,  Suresh, G., Poornima, B., Suresh Babu, K., Ashok Yadav, P., Suri Appa Rao, M.,Siva, B., Rajendra Prasad, K.,Lakshma Nayak. K., Ramakrishna, S., Fitoterapia (2013) 86, 100-107.

[2] Novel malyngamide structural analogs: synthesis and biological evaluation, Venkateswar Reddy, G., Vijaya Kumar, T., Siva, B., Suresh Babu, K., Srinivas, P.V., Sehar, I.,  Saxena, A. K., Madhusudana Rao, J., Medicinal Chemistry Research(2013) 22, 4581–4591.

[1] Formal Total Synthesis of (–)-5,6-Dihydrocineromycine B; Venkateswar Reddy, G., Sateesh, C. K. R., Siva,B., Suresh Babu, K., Madhusudana Rao, J., Synlett (2012) 23, 2677.