Mixed models in quantitative genetics - Module 5 - Swiss institute in statistical genetics

10-12 September 2014 (2,5 days)

Course in collaboration with CUSO Doctoral Program in Ecology & Evolution


Prof. William M. Muir, University of Purdue (USA)

Prof. J. Bruce Walsh, University of Arizona (USA)

Objectives and Content

The analysis of linear models containing both fixed and random effects.

Topics to be discussed include:

  • a basic matrix algebra review,
  • the general linear model, derivation of the mixed model,
  • BLUP and REML estimation,
  • estimation and design issues,
  • Bayesian formulations.

Applications to be discussed include:

  • estimation of breeding values and genetic variances in general pedigrees,
  • association mapping,
  • genomic selection,
  • direct and associative effects models of general group and kin selection,
  • genotype by environment interaction models.

Background reading: Lynch, M. and B. Walsh. 1998. Genetics and analysis of quantitative traits. Sinauer Associates

General information

Date:  10-12 September 2014

Schedule: see course web site

Location: University of Lausanne, Biophore, Amphitheater

Credit point: 1.5 credit point (Research tools)

Evaluation: Full attendance and active participation

Information: Please contact  the CUSO doctoral program coordinator Caroline Betto-Colliard

  • Please bring your laptop to the course!

Registration fee : Free for participants belonging to a CUSO University (UniBE, UniFR, UniGE, UniL & UniNE)

Meals : The DP-biol doctoral program in Organismal biology does not reimburse meals

Travel expenses: For participants of the DP-biol doctoral program in Organismal biology, the train (2nd class, half-ticket) from home University to University of  Lausanne (with city ticket) will be reimbursed (see also more information )


Priority is given to PhD students of the DPEE and the DP-biol until 15 April 2014. After this deadline, first-come, first-served!

Maximum number of participants: 60

!PREREQUISITE!  Have attended the course "Quantitative Genetics".

Online registration on the CUSO doctoral program Ecology and Evolution web site: closed

Deadline: 22 August 2014